CAS 319460-85-0 Axitinib

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CAS 319460-85-0 Axitinib Product Description

Product Name: Axitinib
Synonyms: N-Methyl-2-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide;Benzamide, N-methyl-2-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;UNII-C9LVQ0YUXG;;Inlyta;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;10mg;Axitinib (usan);N-Methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide;AG-013736 N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;Axtinib;AVERMECTINB;Axitinib;N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide;[14C]-Axitinib
CAS NO: 319460-85-0
EINECS: 638-771-6
Molecular Formula: C22H18N4OS
Molecular Weight: 386.47
Melting Point: 213-215°C
Boiling Point: 668.9±55.0 °C(Predicted)
Density: 1.4
Appearance: white to tan Powder
Storage: room temp
Solubility: DMSO: ≥8mg/mL
Applications: A tyrosine kinase inhibitor; used in cancer therapy.

CAS 319460-85-0 Axitinib Products Picture

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CAS 319460-85-0 Axitinib Products Usage

Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.

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